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We also repeated 13 C-glucose flux analysis in the presence of FOXO1 inhibition, demonstrating that the upregulation of glutamine synthesis from glucose (Fig

Hefny A, Fikry AA, Zahran MH, Shendi AM

The primary role of this enzyme is to facilitate the fourth step in pyrimidine synthesis by converting dihydroorotate (DHO) into orotate ( Figure 1 )

Therapeutic potential of glutamine pathway in lung cancer
