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Epithelialmesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI
Epidemiological data have consistently indicated that elevated levels of homocysteine in circulation are associated with an increased risk of cardiovascular disease (56, 57)
FEBS Lett 589:26612667
First-in-Human trials follow a cautious and progressive dose-escalation approach designed to support continuous safety evaluation throughout the study
