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SIRT6 alleviates mitochondrial dysfunction, podocyte injury, and ferroptosis induced by HG through activating the Nrf2/GPX4 pathway and increasing SLC7A11, HO-1, and SOD2 expressions
doi: 10.1007/s002170000189
Ferroptosis is also manifested in the antioxidant system, and it appears that the expression of glutathione peroxidase 4 (GPX4) decreases in the antioxidant system (lipid peroxide) [16-21]
Matsuda N, Lu H, Fukata Y, Noritake J, Gao H, Mukherjee S, Nemoto T, Fukata M, Poo MM (2009) Differential activity-dependent secretion of brain-derived neurotrophic factor from axon and dendrite
