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The downstream metabolites of the kynurenine metabolic pathway, quinolinic and kynurenic acids, are neuroactive metabolites acting on the glutamatergic N -metyl-D-aspartate (NMDA) receptor (57)

Beyond scientific interest, these findings have translational relevance, as modulating adipocyte function or addressing eating behaviors could serve as potential targets for adjunctive therapies in MM (95, 101)

A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use in generally healthy adults

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