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ACEA (arachidonyl-2-chloroethylamide), a selective cannabinoid CB1 receptor agonist, also increases cortical neurons viability exposed to A-42 oligomers, inducing cognitive improvement in APP/PS1 mice

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Monozygotic twin studies, which allow an assessment of the epigenome (gene x environment) independent of underlying genomic sequence mutations, showed high discordance rates and related epigenetic changes [14] in monozygotic twins discordant for psychiatric illnesses