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The serotonin transporter PET ligands 11 C-DASB and 11 C-WAY100635 are useful in identifying individuals at risk of PD prior to the presence of dopaminergic system degradation (Fu et al., 2022
Strategy 2: The Pre-Activity Protocol Now, this is where it gets more specialized
In the presence of HOCl, the first step involves the substitution of chlorine at the C3 position and the addition of water at the C2 position, resulting in the protonated 2-hydroxy-3-chloro intermediate
