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doi: 10.3390/antiox10010009 [DOI] [PMC free article] [PubMed] [Google Scholar] 120

6.2 Potential pathophysiological mechanisms of gut microbiota and metabolite SCFAs in cytokine abnormalities SCFAs (such as acetate, propionate, and butyrate) activate receptors like FFAR2/3 and Gpr109a and inhibit histone deacetylase (HDAC), collectively suppressing the activation of the NF-B signaling pathway, thereby downregulating the expression of pro-inflammatory cytokines (202204)

A Tripeptide from human serum which enhances the growth of neoplastic hepatocytes and the survival of normal hepatocytes

& Kirk, G
