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Repeat step 1, 2, and 3 in order to elute any remaining Ig

doi: 10.4161/derm.24411

We propose that chronic exposure to a particular suite of environmental and genetic factors elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the substantia nigra, striatum, and cerebral cortex, which eventually surfaces as the hallmark features of PD

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