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Description
Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: Specific induction of the promoter in human macrophages by oxidized low-density lipoproteins
67 , 68 The GSH-antibiotic conjugate is more water-soluble and can be expelled, reducing the effective drug concentration
It is a major concern in the elderly and is prevalent in most developed countries

Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria
