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For instance, a hallmark in hemin-induced cytotoxicity (HIC) is the perturbation of proper folding of proteins [58] and the abnormal cross-linking of RBCs major cytoskeletal proteins [59]

Jhurry ND, Chakrabarti M, McCormick SP, Holmes-Hampton GP, Lindahl PA

It also plays a crucial role in maintaining the skin barrier function so that the moisture is locked in, improving the skins appearance