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The best approach is gentle care: avoid vigorous activity, hot heat sources, rubbing the area, and heavy alcohol for a day or two

In HCC cell lines, sorafenib was reported to induce a non-apoptotic form of cell death that was suppressed by lipophilic antioxidants [27, 28], indicating that sorafenib activates ferroptosis in HCC cell lines

Studies have shown that mitochondria-associated ER membranes (MAMs), the ER part directly connected to the mitochondria, participate in the pathogenesis of AKI by regulating calcium signaling, lipid metabolism and energy homeostasis (Igwebuike et al., 2020