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Parameswaran and Patial, 2010)

A phase I study found that the combination of an IDO inhibitor (LY3381916) with anti-PD-L1 increased recruitment of CD8+ T cells in the TME, leading to disease stabilization in cancer patients (141)

CX-4945 and TBB inhibit CK2 [28], which phosphorylates a variety of proteins that regulate DDR, circadian rhythms, cell survival, senescence, and apoptosis
