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Description
GR has a significant auxiliary AO function related to GSHPX and GST
injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages), 300 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) in comparison with vehicle-treated age-matched chow-fed C57BL/6 J mice ( n = 16 mice and n = 8-11 cages) for 14 days
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Phase 2 data showed mean weight loss of up to 24.2% at 48 weeks, which, if confirmed in phase 3 trials, would surpass both CagriSema and tirzepatide
