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[PMC free article: PMC3171935] [PubMed: 21804091] 899

Hanson, G

Molecular studies indicate that, in those afflicted, there is a higher likelihood for the riboflavin cofactor (FAD) to separate from the enzymes active site, causing it to become inactive, resulting in poor folate metabolism [96]

Chemicals in this group are usually negative in vivo and non-DNA-reactive