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Growth hormone, interleukin- (IL-1), and TNF- affect secretion of IGF-1whereas IGF-2 is affected by TNF- only
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Where possible, avoid suddenly reducing the B 12 dose or injection frequency, as too rapid dose reduction may worsen symptoms or lead to symptom recurrence.26 Instead, gradually increase the interval between B 12 injections over the course of several months while monitoring symptoms
British Journal of Clinical Pharmacology, 40(3), 237-243
