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Symonds, D

The study concluded that long-term antioxidant therapy with NAC helped prevent the development of pre-diabetes, dyslipidemia, and liver inflammation in obese rats, largely by reducing oxidative stress

Available data suggest that these substances are capable of crossing the BBB (Zhang et al., 1998

In line with this, various experiments using cell cultures, transgenic mice, and preclinical models revealed protective effects of antioxidants (Polidori and Nelles 2014