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Bakker J, Nijsten MW, Jansen TC

These patients experience accumulation of plasma acylcarnitines, in part due to a decreased renal clearance of esterified carnitine moieties [54]

In addition, when circulating L-carnitine concentration increases, as in the case of oral supplementation, renal reabsorption of L-carnitine may become saturated, resulting in increased urinary excretion of L-carnitine (5)

However, taking excessive amounts or ignoring proper timing may lead to mild discomfort
