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Description
The compound's interaction with VEGFR2 triggers rapid autophosphorylation of tyrosine residues 1175 and 1214, essential for subsequent recruitment of adaptor proteins including Grb2 and Shc

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In a head-to-head study of the two agents sponsored by Eli Lilly, makers of tirzepatide, found a 20.2% weight loss with tirzepatide compared to a 13.7% weight loss with semaglutide

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