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The patient was managed with parenteral vitamin B12 injections, folic acid, PPIs, and supportive therapy, along with aminosalicylates and systemic corticosteroids after confirmation of inflammatory bowel disease
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While direct evidence linking the RARA::RXRA and RARA::RXRG complexes to CCL11 expression in the CNS is currently not well established, it is plausible to speculate that retinoic acid signaling through these complexes could inhibit CCL11 expression in specific brain conditions
