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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Landazuri P., Granobles C., Loango N
10.1155/2022/8287227 175 ZhengJ.ConradM
The GHR belongs to the class 1 cytokine receptors which uses STAT as one of its principal secondary messengers, and the subsequent phosphorylation of two STAT5b molecules results in a phospo-STAT5b homodimer which translocate to the cell nucleus, binds to STAT5b recognition sites on the IGF1 gene promoter, and initiates transcription (Figure 3)
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