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The prostate gland exhibits unique metabolic features characterized by extraordinary citrate production (up to 180 mM in prostatic fluid) to support sperm energetics, sustained through zinc-mediated inhibition of mitochondrial aconitase(m-ACNT), which blocks citrate-to-isocitrate conversion (71)
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While effective for some, adherence can be a challenge due to the nature of this mechanism
10.1016/j.alcohol.2009.02.001 105.Mackillop J , Menges DP , McGeary JE , Lisman SA
