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Collectively, these data indicate that combined loss of PHD2 and GSTP1 precipitates a metabolic and apoptotic collapse consistent with a synthetic lethal interaction

2018;57(3):e201

However, it is usually used in combination with levodopa to reduce associated extrapyramidal manifestations and enhance dyskinesia [42]

Overall, the authors concluded that NAC might be useful as a chemopreventive agent
