glutathione pancreatic cancer How survives ferroptosis? Pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations exhibit relative resistance to iron-dependent form of cell death, ferroptosis, compared with other tumor types but the mechanisms remain KRAS/ACTN4/p65-NR2A axis mediates glutamine-glutamate metabolic
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10.1111/and.12135 [DOI] [PubMed] [Google Scholar] Muoz, P
Wilson disease: Copper everywhere Wilson disease is caused by mutation of the ATP7B gene, which results in impaired copper excretion and accumulation of toxic levels of copper in many organs principally the liver, brain, and eye
In fact, some studies have used much higher doses for short periods without observing serious adverse effects
USA 101 , 847852 (2004)
