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mRNA expression studies at 1 and 24 hr, provided strongly elevated ( Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos3, and Nos1 ) and decreased ( Nos2, Nfkb ) gene expression ( Mapk1 not activated), as a way how BPC 157 may act
TFAM proteins bind to the light and heavy chain promoter regions of DNA (Zorzano and Claret, 2015), increasing the flexibility of DNA and promoting its compression (Malarkey et al., 2016)
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