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In fact, research shows that testosterone may actually improve antidepressant effectiveness, as well as function in an antidepressant capacity itself: In one 2015 study, researchers found that transgender people taking high dose testosterone supplementation had increased serotonin reuptake transporter binding

However, taking megadoses of some water-soluble vitamins can lead to potentially dangerous side effects

The systematic review of various evidence and studies suggests that a higher dietary intake of B vitamins could lower the risk of advanced macular degeneration