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Images were captured using a LSM 980 with Airyscan2 confocal microscope (Carl Zeiss Meditec AG, Jena, Germany)
However, the lack of targeting of PLGA NPs and the wide variation in brain uptake efficiency by different routes of administration limit the therapeutic efficacy of loaded drugs
B-Complex (B1, B5, B6): Promotes metabolism, adrenal support, and stress balance
Conversely, a phase II trial in relapsed germ cell tumors showed no restored cisplatin sensitivity, with median progression-free survival (PFS) and OS of only 1.4 and 2.9 months, respectively [275]
