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According to the redox theory of aging, the ratios of GSH/GSSG and NADP+/NADPH levels are important factors that may affect longevity by modulating the cellular redox status [140]
Valori CF, Ning K, Wyles M, et al
Healthcare utilization in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Analysis of US ambulatory healthcare data, 20002009
However, drugs targeting the corresponding metabolic pathways not only impact tumor cells but also exert effects on healthy proliferating cells, potentially leading to significant adverse reactions
