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(70) have demonstrated increased -globin minor (a mouse -globin gene duplication product) and a complete absence of -globin in stimulated macrophages

Possible reasons could be that (1) DAB is preferred by LaccID over other aromatic substrates, and (2) DAB labeling was performed in sodium cacodylate buffer, which does not contain laccase inhibitors such as halides and thiols

doi: 10.1016/j.redox.2020.101480 [DOI] [PMC free article] [PubMed] [Google Scholar] [90].Finaud J, Lac G, Filaire E

I think when you look at the fact that depression is so strongly correlated to altitude, I think thats a big signal and just the role of serotonin in handling hypoxia