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10.1007/s11033-011-0749-7 171 WeiL.JianH.LuK.FilardoF.YinN.LiuL.et al

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In addition to the indirect consequences of long-term oral antibiotic consumption on intestinal barrier health, particularly through reducing the numbers of SCFA-producing species, these therapeutics have also been reported to directly impair the gut barrier by reducing the expression of TJ proteins and negatively impacting their morphology