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Various monoclonal antibodies have been developed to block c-Met/HGF signaling pathways, some of which competitively bind to c-Met, and the others are served as traps for c-Met, preventing ligand attachment and dimerization of c-Met [168]

Nature 472, 476480

Next, 900 l serum extract was dried in a vacuum evaporator (Thermo), reconstituted in 90 l of 50% acetonitrile (A955, Fisher Scientific) and transferred to glass vials for LCMS analysis

Diabetes is classified into two types: Type 1, an autoimmune disorder in which the pancreas produces little or no insulin, and Type 2, which is characterized by insulin resistance and/or impaired insulin secretion