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a: significance between the control and APAP, groups ( p -value = 0.001), b: significance between the PA, and APAP, groups ( p -value = 0.001), c: significance between the APAP and APAP + PA groups ( p -value = 0.008)

In addition, they also documented several immunity and immunity linked biological signaling pathways (B cell receptor signaling pathways, TNF signaling pathway, IL-17 signaling pathway and NF-B signaling pathway) which is in consistent with findings reported previously (165, 173)

Abbreviations S: Alpha-synuclein the major constituent of Lewy bodies and a pathogenic hallmark of all synucleinopathathies PD: Parkinsons disease DLB: dementia with Lewy bodies MSA: multiple system atrophy SNCA: SyNuClein Alpha gene that codes for the S protein References Ou Z, Pan J, Tang S, Duan D, Yu D, Nong H, Wang Z