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Description
Effect of treatment on the number and size of bound GTP vesicles and rapid Nrf2 activation in 3xTg-AD hippocampal neurons We hypothesized that impaired vesicular endocytosis was caused by an energy shortage that resulted in a buildup of vesicles and possibly enlargement from failure to complete processing

Western blotting and subsequent immunodetection of carbonylated proteins were performed according to the protocol recommended by the manufacturer (see material and methods)

16 weeks (titration phase) 2-3 x 10 mg vials 2.5 5 7.5 mg weekly through Week 16

This simple practice helps ensure the tissue stays healthy and can properly absorb the vitamin every time
