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Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration

This recognition can enhance phagocytic capacity or activate the secretion of pro-inflammatory cytokines ( 2.3 Mechanisms of macrophage-mediated myocardial injury Activated macrophages exacerbate SRMI through multiple, highly synergistic molecular mechanisms that extend far beyond simple cytokine release

Lancet Neurol (2021) 20(1):6880

It catalyzes the conversion of free long-chain fatty acids into acyl-CoA derivatives, facilitating their integration into cell membranes ( 2.1.4 Iron-responsive element-binding protein 2 Other molecules involved in lipid and iron metabolism also regulate ferroptosis, including iron-responsive element-binding protein 2 (IRP2) ( 2.2 Organelle-specific regulation of ferroptosis Organelle interactions are fundamental to the regulation of ferroptosis and include various cellular compartments such as mitochondria and the endoplasmic reticulum (ER), which work in conjunction with lipid metabolic pathways ( Figure 2 )
