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The ferroptosis pathway is enriched at both 4 and 8 weeks after chronic compression SCI, and MDA content peaked at 4 weeks after chronic compression, decreased at 8 weeks, and was negatively correlated with behavioral scores
[DOI] [PubMed] [Google Scholar] 195.Nussbaum RL
In summary, levodopa offers favorable brain delivery but has an inconveniently short duration of action, whereas many natural compounds possess inherently longerlasting effects but encounter challenges in absorption and brain penetration (Figure 7)
