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Dismissing such studies in favor of lower-quality evidence with greater potential for bias represents a fundamental rejection of evidence-based principles (Guyatt et al., 2008[47]

The American and Canadian Colleges of Obstetrics and Gynecology recommend the use of a delayed-release formulation of pyridoxine hydrochloride (vitamin B 6 ) plus doxylamine succinate (an antihistamine) as first-line therapy for nausea and vomiting during pregnancy

2018;174:10381038.e1031

Researchers commonly use 1mL or 2mL of bacteriostatic water
