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Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils

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Additionally, certain enzymes rely on thiol groups for their catalytic mechanisms, wherein the sulfhydryl moiety acts as a nucleophile or participates in substrate binding

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Confirming these observations, studies from our lab showed that protein oxidation by UVA irradiation also affects the ability of human cells to replicate their genetic material, probably due to translesion synthesis (TLS) and NER being affected in irradiated XP-V cells (Moreno et al

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