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Requirement of lectin domain in efficient enzyme reaction To investigate the functions of the GnT-IVa lectin domain in more detail, we purified soluble wild-type enzyme and its D445A mutant (Fig

2022;61(Suppl 2):65-74

Therefore, we asked whether we could rescue glutamine dependency of KPK cells by forcing the export of cystine and the import of glutamate by modulating the concentration of these two amino acids in the culture media

Finally, NAC supports the Nrf2-dependent transcription pathway, a genetic cellular defense mechanism that upregulates the production of endogenous antioxidant enzymes, providing a robust buffer against the oxidative damage to DNA, proteins, and lipids that naturally occurs with aging and chronic illness