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141,146,147 Glutamine metabolism Glutamine metabolism is a major cellular carbon source for the TCA cycle, a nitrogen donor for nucleotide, amino acid, and lipid biosynthesis, it is also critical for maintaining NADPH levels
The RNA of low-grade selenoproteins degrades rapidly during selenium deficiency, while the RNA of high-grade selenoprotein remains stable, resulting in increased selenium reuse and faster resynthesis of selenoproteins (Banning et al., 2008b).In the GPX family with Sec as the active center, GPX2 has the highest rating, followed by GPX4, GPX3 and GPX1 (Banning et al., 2008b)
12,13,14,15 The principal Cu chaperones include COX17 (which delivers Cu to cytochrome c oxygenase), CCS (Cu chaperone for superoxide dismutase, which delivers Cu to superoxide dismutase 1), and ATOX1 (which delivers Cu to ATP7A and ATP7B)

Conlon MA, Bird AR
