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These preclinical results led to a clinical trial in chronic lymphocytic leukemia (CLL), where chlorambucil-resistant patients achieved further remission through ethacrynic acid cotreatment with the alkylating agent (Petrini et al ., 1993)

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Denecke J, Dewenter A, Lee J et al (2025) Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease

As expected, temporal changes in lipolysis per cell were closely correlated with changes in adipocyte volume