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If our data based on an intense and short exposure to HNE can be extended to an in vivo situation where low concentrations of HNE are produced on a long time scale, the present results suggest that although the amount of DNA adducts is low upon treatment by exogenous HNE, their formation could be favored upon oxidative stress

Elisa DellAglio1 and Amna Mhamdi2 1 Institut National des Sciences Appliques-Lyon, 69100 Villeurbanne, France 2 Ghent University, Department of Plant Biotechnology and Bioinformatics

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