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LC 50 for K1 cells was ~ 0.4 M, whereas RSL3 treatment did not significantly affect TPC-1 cell viability, suggesting RSL3 selectively inhibits RAS/BRAF -mutant cell lines, such as K1, MDA-T32, and MDA-T68 (Fig
In support of this theory, NOX2-deficient mice are protected from cognitive decline associated with sleep fragmentation [39]
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Mansoor et al
