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Description
Ellis CE
Though only a fraction of total CHAC1 is associated with the mitochondria in our cells, we show that mitochondrial CHAC1 supports the matrix cysteine pool and is sufficient to sustain Fe-S protein activity under cystine starvation
Cortisol, a glucocorticoid hormone, is known to have neurotoxic effects when present in excess
Notably, GSH depletion did not further decrease lipid accumulation in these knockdown conditions, indicating a lack of additive effect
