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doi:10.3322/caac.21772 Stoffel EM, Murphy CC
On the contrary, an increase in macrophage infiltration into DRGs did occur after repeated oxaliplatin administration, where both neurons and macrophages secreted matrix metallopeptidase (MMP) 9-2 (proteolytic enzymes involved in neuroinflammation and chronic pain), by activating TLR4 through HMGB1 protein
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