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In animal models, L-carnitine increases bone mineral density and decreases bone resorption

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Food sources rich in l-carnitine are animal products, particularly beef and pork

In the TMLHE gene knockout mouse model, the carnitine biosynthetic pathway is inhibited due to the loss of TMLD activity in the liver, affecting the availability of carnitine in the heart, significantly reducing the rate of synthesis of LCACs, and contributing to the protection of mitochondrial function after myocardial IRI [215]