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Description
(2021) 149:106410.10.1016/j.envint.2021.106410 11

Oxygen toxicity Discovery of oxygen toxicity Although organisms have developed complex mechanisms to adapt to hypoxia (such as HIF and HIFPHD signalling), given that atmospheric oxygen concentrations that are higher than current levels are rarely encountered, land mammals are less well equipped to adapt to hyperoxia 45

95 Remifentanil, although rapidly cleared even in cases of organ dysfunction, quickly induces tolerance and opioid-induced hyperalgesia
Adjust for a 1,500 mg kit (~15 doses) or 50 mg dose (~15 doses per 750 mg vial)
