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Given the above, employing bioinformatics approaches, efforts were made in this study (a) to identify potential GPX and APX genes/proteins from 18 different plant species, (b) to analyze their exon/intron organization, (c) to provide detailed information about their physico-chemical properties, (d) to identify conserved motif signatures of GPX and APX, (e) to construct their phylogenetic trees and 3D models, (f) to generate protein-protein interaction networks, and finally (g) to analyze GPX and APX gene expression profiles

The mechanism appears unrelated to the lipolytic pathway

Hsieh T-C, Wu JM (2011) Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3