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Clinical trials in epileptic patients under antiepileptic medication found that 90 days of acetyl-L-carnitine supplementation significantly improved memory quotient and word fluency tests compared to placebo, indicating benefits for frontal lobe and memory function independent of direct anticonvulsant effects

Two uncontrolled studies conducted in participants with cirrhosis found that L-carnitine supplementation was safe to use at doses of 0.9 to 1.2 g/day for eight weeks (125) and 1 g/day for 24 weeks (126) and might be considered to control the frequency of cramps

Endocrinology 149 , 29592969 (2008)

Unfortunately, this nutrient becomes less concentrated in bone along with osteocalcin, a protein secreted by osteoblasts that is involved in bone mineralization