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In this long-term study, patients with moderate to severe nonproliferative diabetic retinopathy who received ruboxistaurin for 5 years versus 2 years had a much lower incidence of SMVL (8% versus 26%)

Scoring of neovaginal smears was performed alongside smears collected from the natal vagina (from a separate study), by a single investigator who was blinded to the origin of the smear

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doi: 10.1097/00002826-200003000-00010
