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Description
At least 20 animals were recorded per strain or treatment and the average body bends per minute for each of the samples was calculated and graphed using GraphPad Prism 8.0 ( Resistance to oxidative stress Paraquat plates were made by adding 1 mL of 250 mM paraquat solution to corresponding treatment plates

For the optic nerve crush rat models, the RGC shows a reduction of GPX4 and SLC7A11 expression, increased membrane density, reduced mitochondrial cristae, and increased lipid peroxide and iron levels, indicating RGC ferroptosis after optic nerve crush (Guo et al., 2022)

Edlinger A, Garland G, Hartman K, Banerjee S, Degrune F, Garca-Palacios P, Hallin S, Valzano-Held A, Herzog C, Jansa J, Kost E, Maestre FT, Pescador DS, Philippot L, Rillig MC, Romdhane S, Sagha A, Spor A, Frossard E, van der Heijden MGA (2022) Agricultural management and pesticide use reduce the functioning of beneficial plant symbionts

When these antioxidants are stretched too thin, hydrogen peroxide accumulates
