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10.1227/NEU.0000000000000341 Neurosurgery Summary Keywords traumatic brain injury (TBI), chronic traumatic encephalopathy (CTE), animal models of TBI, stress, neuroinflammation, calcium dysregulation, tauopathy Citation Fesharaki-Zadeh A and Datta D (2024) An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms